Author

R. M. Hekman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

A. Emili· 4 shared M. Ericsson· 3 shared A. K. O'Connell· 2 shared B. Blum· 2 shared D. N. Kotton· 2 shared E. Bullitt· 2 shared F. Douam· 2 shared J. H. Connor· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersMicrobiology

A. Emili

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Platelet proteome analysis reveals an early hyperactive phenotype in SARS-CoV-2-infected humanized ACE2 mice

S. Subramaniam, R. M. Hekman, A. Jayaraman, A. K. O'Connell, P. Montanaro, B. Blum, D. Kenney, M. Ericsson, K. Ravid, N. A Crossland, A. Emili, F. Douam, M. Bosmann

This paper uses proteomics to analyze platelet changes in SARS-CoV-2-infected humanized mice, finding early activation of coagulation and complement pathways.

bioRxiv · Aug 19, 2021 · PreprintImmunology

Recombinant Lloviu virus as a model to study inaccessible zoonotic viruses

A. J. Hume, B. Heiden, J. Olejnik, E. L. Suder, S. Ross, W. A. Scoon, E. Bullitt, M. Ericsson, M. R. White, J. Turcinovic, T. T. N. Thao, R. M. Hekman, J. E. Kaserman, J. Huang, K. Alysandratos, , E. Mühlberger

This study uses recombinant Lloviu virus to investigate replication mechanisms and host interactions of an uncultured filovirus related to Ebola.

bioRxiv · Aug 2, 2021 · PreprintMicrobiology

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease

K.-D. Alysandratos, S. J. Russo, A. Petcherski, E. P. Taddeo, R. Acin-Perez, C. Villacorta-Martin, J.-C. Jean, S. Mulugeta, B. C. Blum, R. M. Hekman, M. Vedaie, S. Kook, J. A. Wambach, F. S. Cole, A. Hamvas, , D. N. Kotton

This study uses patient-derived iPSCs with an SFTPC mutation to model early alveolar epithelial dysfunction in interstitial lung disease, revealing proteostasis, metabolic, and inflammatory changes.

bioRxiv · Nov 13, 2020Cell Biology