USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING
R. Karlowitz, M. L. Stanifer, J. Roedig, G. Andrieux, D. Bojkova, S. Smith, L. Kowald, R. Schubert, M. Boerries, J. Cinatl, S. Boulant, S. J. van Wijk
This study identifies USP22 as a regulator of STING and type III IFN signaling, showing its role in SARS-CoV-2 infection and antiviral defense in human intestinal epithelial cells.
bioRxiv · Feb 1, 2022Cell Biology