Author

A. E. Dubin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:Arabidopsis· 2 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Patapoutian· 3 shared A. B. Ward· 2 shared W.-H. Lee· 2 shared A. M. Coombs· 1 shared C. A. Cottrell· 1 shared C. Ge· 1 shared C. S. Crowley· 1 shared D. A. Ghadiri· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPhysiology

A. Patapoutian

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Renal mechanotransduction is an essential regulator of renin

R. Z. Hill, S. Shirvan, S. Burquez, A. E. Dubin, M. R. Servin Vences, J. H. Miner, A. Patapoutian

This study identifies PIEZO2 as a mechanotransducer in juxtaglomerular cells that regulates renin release and blood pressure.

bioRxiv · Nov 4, 2023 · PreprintPhysiology

Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli

S. Jojoa-Cruz, A. E. Dubin, W.-H. Lee, A. B. Ward

The paper identifies structural elements in OSCA channels that differentially mediate stretch and poking activation through mutagenesis and electrophysiology.

bioRxiv · Oct 3, 2023Biochemistry

PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana

A. Patapoutian, S. A. R. Mousavi, A. E. Dubin, W.-Z. Zeng, A. M. Coombs, K. Do, D. A. Ghadiri, Y. Zhao, C. Ge

This study identifies PIEZO as a mechanosensitive ion channel in Arabidopsis roots, showing its role in mechanotransduction and mechanical stress response.

bioRxiv · Aug 27, 2020Plant Biology

Structure of the Human Volume Regulated Anion Channel

J. M. Kefauver, K. Saotome, A. E. Dubin, J. Pallesen, C. A. Cottrell, G. Hong, S. M. Cahalan, Z. Qiu, C. S. Crowley, T. Whitwam, W.-H. Lee, A. B. Ward, A. Patapoutian

The paper reports the high-resolution cryo-EM structure of human SWELL1, revealing its trimer of dimers assembly and identifying a charged residue critical for pore function in VRAC.

bioRxiv · May 16, 2018Biochemistry