S. K. Burley

Outcome of Crash Course Training on Protein Structure Prediction with Artificial Intelligence

This paper summarizes a crash course on AI-driven protein structure prediction, highlighting its global reception and organizational insights.

Assessing PDB Macromolecular Crystal Structure Confidence at the Individual Amino Acid Residue Level

The paper evaluates the confidence of individual amino acid residues in PDB macromolecular crystal structures using RSCC and compares it to AlphaFold2's pLDDT scores, finding RSCC better reflects experimental reliability.

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

The paper generates structural models of the SARS-CoV-2 Omicron variant bound to ACE2 and antibodies, revealing altered binding interfaces and neutralization escape mechanisms.

Apropos of Universal Epitope Discovery for COVID-19 Vaccines: A Framework for Targeted Phage Display-Based Delivery and Integration of New Evaluation Tools

The paper describes a framework using targeted phage display to identify conserved epitopes on the SARS-CoV-2 Spike protein for universal vaccine development.

Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain

This paper designs and evaluates phage-based and AAVP-based vaccination strategies for SARS-CoV-2 that induce systemic antibody responses in mice, with potential for a cold-free supply chain.