Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro
R. Yadav, V. V. Courouble, S. K. Dey, J. J. E. K. Harrison, J. Timm, J. B. Hopkins, R. L. Slack, S. G. Sarafianos, F. X. Ruiz, P. R. Griffin, E. Arnold
The paper elucidates the structural basis and cleavage order of SARS-CoV-2 nsp7-11 polyprotein processing by Mpro, with implications for Mpro inhibition.
bioRxiv · May 27, 2022Biochemistry