Hepatocyte-Targeted siTAZ Therapy Lowers Liver Fibrosis in NASH Diet-Fed Chimeric Mice with Hepatocyte-Humanized Livers
X. Wang, M. P. Moore, H. Shi, Y. Miyata, S. K. Donnelly, D. R. Radiloff, I. Tabas
bioRxiv · Oct 27, 2023Pharmacology & Toxicology
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X. Wang, M. P. Moore, H. Shi, Y. Miyata, S. K. Donnelly, D. R. Radiloff, I. Tabas
bioRxiv · Oct 27, 2023Pharmacology & Toxicology
M. Hülsemann, S. K. Donnelly, P. V. Verkhusha, S. S. P. H. Mao, J. E. Segall, L. Hodgson
This study shows TC10 regulates breast cancer invasion and metastasis by controlling MT1-MMP activity at invadopodia through p190RhoGAP and Exo70.
bioRxiv · Nov 17, 2020Cell Biology