Author

L. Hodgson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. D. Davidson· 2 shared J. E. Segall· 2 shared A. Saraswathibhatla· 1 shared A. Tobi· 1 shared B. C. H. Cheung· 1 shared B. M. Collins· 1 shared B. Simonetti· 1 shared C. Anton-Plagaro· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

A. D. Davidson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification of CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices

B. C. H. Cheung, X. Chen, H. J. Davis, C. S. Nordmann, J. Toth, L. Hodgson, J. E. Segall, V. B. Shenoy, M. Wu

This study identifies CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices, showing its role in modulating collagen network mechanics and tumor invasion.

bioRxiv · Oct 24, 2023 · PreprintBiophysics

Collective invasion of the basement membrane in breast cancer driven by forces from cell volume expansion and local contractility

J. Chang, A. Saraswathibhatla, Z. Song, S. Varma, C. Sanchez, S. Srivastava, K. Liu, M. C. Bassik, M. P. Marinkovich, L. Hodgson, V. Shenoy, R. B. West, O. Chaudhuri

This study shows breast cancer cells invade the basement membrane using both proteases and mechanical forces from cell volume expansion and local contractility.

bioRxiv · Jul 28, 2022 · PreprintCancer Biology

The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron

C. Toelzer, K. Gupta, S. K. N. Yadav, L. Hodgson, M. Kavanagh Williamson, D. Buzas, U. Borucu, K. Powers, R. Stenner, K. Vasileiou, F. Garzoni, D. Fitzgerald, C. Payre, G. Lambeau, A. D. Davidson, , C. Schaffitzel

The paper identifies a conserved free fatty acid-binding pocket in pathogenic β-coronavirus spike proteins that suppresses viral infection and replication.

bioRxiv · Apr 22, 2022Biochemistry

ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1

B. Simonetti, J. L. Daly, L. Simon-Gracia, K. Klein, S. Weeratunga, C. Anton-Plagaro, A. Tobi, L. Hodgson, P. Lewis, K. J. Heesom, D. K. Shoemark, A. D. Davidson, B. M. Collins, T. Teesalu, Y. Yamauchi, P. J. Cullen

The paper identifies Neuropilin-1 as a retrograde cargo of ESCPE-1 and shows ESCPE-1 mediates its trafficking, potentially facilitating SARS-CoV-2 infection.

bioRxiv · Jan 20, 2022Cell Biology

TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia

M. Hülsemann, S. K. Donnelly, P. V. Verkhusha, S. S. P. H. Mao, J. E. Segall, L. Hodgson

This study shows TC10 regulates breast cancer invasion and metastasis by controlling MT1-MMP activity at invadopodia through p190RhoGAP and Exo70.

bioRxiv · Nov 17, 2020Cell Biology