Y. Miyata

Hepatocyte-Targeted siTAZ Therapy Lowers Liver Fibrosis in NASH Diet-Fed Chimeric Mice with Hepatocyte-Humanized Livers

A Sodium-dependent Trehalose Transporter Contributes to Anhydrobiosis in Insect Cell Line, Pv11

This paper identifies STRT1, a sodium-dependent trehalose transporter in Pv11 cells, which is essential for recovery from anhydrobiosis by regulating intracellular osmolality during rehydration.

Identification of FAM53C as a cytosolic-anchoring inhibitory binding protein of the kinase DYRK1A

This study identifies FAM53C as a novel inhibitor of DYRK1A kinase activity and cytoplasmic anchor, revealing its role in regulating DYRK1A's localization and function.

Development of a Tet-On inducible expression system for the anhydrobiotic cell line, Pv11

The paper develops a Tet-On inducible expression system for the desiccation-tolerant Pv11 cell line, demonstrating successful expression of reporter genes and a complex enzyme.

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

This paper evaluates the safety and efficacy of Avaren-Fc, a HCV-targeting lectibody, in a human liver chimeric mouse model, showing it prevents HCV infection without toxicity.