Author

J. E. Segall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

L. Hodgson· 2 shared A. Lu· 1 shared A. T. Madsen· 1 shared B. C. H. Cheung· 1 shared B. S. Wong· 1 shared C. Montagna· 1 shared C. S. Nordmann· 1 shared D. Zheng· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiophysics

L. Hodgson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices

B. C. H. Cheung, X. Chen, H. J. Davis, C. S. Nordmann, J. Toth, L. Hodgson, J. E. Segall, V. B. Shenoy, M. Wu

This study identifies CD44 as a key mediator of cell traction force generation in hyaluronic acid-rich extracellular matrices, showing its role in modulating collagen network mechanics and tumor invasion.

bioRxiv · Oct 24, 2023 · PreprintBiophysics

Functional Contribution of Cancer-Associated Fibroblasts in Glioblastoma

P. M. Galbo, Y. Liu, M. Peng, Y. Wei, A. T. Madsen, S. Graff, C. Montagna, J. E. Segall, S. Sidoli, X. Zang, D. Zheng

This study identifies and characterizes cancer-associated fibroblasts (CAFs) in glioblastoma using single-cell RNA sequencing and spatial transcriptomics, revealing their functional roles in tumor progression and microenvironment interactions.

bioRxiv · Apr 7, 2022 · PreprintCancer Biology

TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia

M. Hülsemann, S. K. Donnelly, P. V. Verkhusha, S. S. P. H. Mao, J. E. Segall, L. Hodgson

This study shows TC10 regulates breast cancer invasion and metastasis by controlling MT1-MMP activity at invadopodia through p190RhoGAP and Exo70.

bioRxiv · Nov 17, 2020Cell Biology

Post-EMT: Cadherin-11 mediates cancer hijacking fibroblasts

W. Kang, Y. Fan, Y. Du, E. A. Tonkova, Y.-H. Hsu, K. V. Tan, S. Alexander, B. S. Wong, H. Yang, J. Luo, K. Yao, J. Yang, X. Hu, T. Liu, Y. Gan, , Z. Gu

This study identifies cadherin-11 as a mediator of cancer cell hijacking of fibroblasts post-EMT, enhancing invasion and metastasis in solid tumors.

bioRxiv · Aug 27, 2020 · PreprintCancer Biology