Author

S. K. Kuncha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Bhattacharya· 2 shared I. Dikic· 2 shared M. Misra· 2 shared R. Mukherjee· 2 shared R. Rathore· 2 shared R. Sankaranarayanan· 2 shared S. B. Routh· 2 shared A. Balakrishnan· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

A. Bhattacharya

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Author profile →

5 papers

Recent·Most cited

Serine ubiquitination of p62 regulates Nrf2 dependent redox homeostasis

R. Mukherjee, M. Hoffmann, A. Gonzalez, A. Bhattacharya, S. K. Kuncha, R. Rathore, D. Shin, T. Colby, I. Matic, M. Misra, I. Dikic

This study shows that serine ubiquitination of p62 by Legionella pneumophila SidE effectors inhibits Nrf2 signaling, altering redox homeostasis and host metabolism during infection.

bioRxiv · Jun 17, 2023 · PreprintCell Biology

The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways

R. Berkane, H. Ho-Xuan, M. Glogger, P. Sanz-Martinez, L. Brunello, T. Glaesner, S. K. Kuncha, K. Holzhueter, S. Cano-Franco, V. Buonomo, P. Cabrerizo-Poveda, A. Balakrishnan, M. Misra, T. Juretschke, K. Husnjak, , A. Stolz

This study identifies CK2-dependent phosphorylation and ubiquitination as essential for FAM134B and FAM134C-driven ER-phagy activation during mTOR inhibition.

bioRxiv · Feb 27, 2023Cell Biology

TBC1D15 potentiates lysosomal regeneration from damaged membranes

A. Bhattacharya, R. Mukherjee, S. K. Kuncha, M. Brunstein, R. Rathore, S. Junek, C. Munch, I. Dikic

The paper identifies TBC1D15 as a key regulator of lysosomal regeneration from damaged membranes through a pathway involving LIMP2, ATG8, and ALR components.

bioRxiv · Dec 14, 2022 · PreprintCell Biology

A discriminator code-based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria

R. Sankaranarayanan, S. K. Kuncha, K. Suma, K. I. Pawar, J. Gogoi, S. B. Routh, S. Pottabathini, S. P. Kruparani

The paper shows DTD discriminates tRNA discriminator bases to ensure correct glycine delivery in bacteria, with eukaryotic DTD using inverted specificity.

bioRxiv · May 14, 2018Biochemistry

A Chiral Selectivity Relaxed Paralog Of DTD For Proofreading tRNA Mischarging In Animalia

S. K. Kuncha, M. Mazeed, R. Singh, B. Kattula, S. B. Routh, R. Sankaranarayanan

The paper identifies ATD, a chiral-selective variant of DTD in Animalia, which proofreads L-alanine mischarged on tRNA and is conserved across Chordata.

bioRxiv · Jun 8, 2017Biochemistry