Author

R. B. Altman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. C. Blanchard· 2 shared A. Schepartz· 1 shared B. Chen· 1 shared C. Re· 1 shared D. W. B. Broadwater· 1 shared E. Fast· 1 shared F. A. Cruz Navarrete· 1 shared F. Wang· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

S. C. Blanchard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

β-amino acids reduce ternary complex stability and alter the translation elongation mechanism

F. A. Cruz Navarrete, W. C. Griffin, Y.-C. Chan, M. I. Martin, J. L. Alejo, S. K. Natchiar, I. Knudson, R. B. Altman, A. Schepartz, S. J. Miller, S. C. Blanchard

This study investigates how β-amino acid isomers affect ternary complex stability and translation elongation by analyzing their impact on ribosome function and EF-Tu interactions.

bioRxiv · Feb 24, 2024Biochemistry

Single-cell analysis of non-alcoholic fatty livers identifies a role for the constitutive androstane receptor

L. Coassolo, T. Liu, Y. Jung, N. P. Taylor, M. Zhao, G. W. Charville, S. B. Nissen, H. Yki-Jarvinen, R. B. Altman, K. J. Svensson

The paper uses single-cell RNA sequencing to identify lipid synthesis clusters and links the constitutive androstane receptor to hepatic steatosis in NAFLD.

bioRxiv · Aug 15, 2022 · PreprintCell Biology

Potential T-cell and B-cell Epitopes of 2019-nCoV

E. Fast, R. B. Altman, B. Chen

This paper identifies potential T-cell and B-cell epitopes of 2019-nCoV using computational methods, finding mutations in antigen-presenting regions and a spike protein epitope that may trigger immune responses.

bioRxiv · Feb 19, 2020 · PreprintMicrobiology

Classifying Non-Small Cell Lung Cancer Histopathology Types and Transcriptomic Subtypes using Convolutional Neural Networks

K.-H. Yu, F. Wang, G. J. Berry, C. Re, R. B. Altman, M. Snyder, I. S. Kohane

This study uses convolutional neural networks to classify non-small cell lung cancer histopathology types and transcriptomic subtypes using whole-slide images from The Cancer Genome Atlas.

bioRxiv · Jan 25, 2019Pathology

ERASE: a novel surface reconditioning strategy for single-molecule experiments

D. W. B. Broadwater, R. B. Altman, S. C. Blanchard, H. D. Kim

The paper introduces ERASE, a method to reuse single-molecule experiment surfaces by removing biomolecules via DNA strand displacement, enabling repeated use and parallel molecule analysis.

bioRxiv · Mar 15, 2018Biophysics