Author

S. Kaptein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Neyts· 2 shared R. Abdelnabi· 2 shared B. Weynand· 1 shared C. Montpellier· 1 shared C. S. Foo· 1 shared D. Jochmans· 1 shared J. Rocha-Pereira· 1 shared J. Van Dycke· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

J. Neyts

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Proliferative cell targeting and epithelial cell turnover fuels hepatitis E virus replication in human intestinal enteroids

N. Santos-Ferreira, X. Zhang, L. Corneillie, J. Van Dycke, W. Chiu, C. Montpellier, J. Neyts, L. Cocquerel, S. Kaptein, J. Rocha-Pereira

This study establishes an HEV-HIE model showing HEV replication in intestinal epithelial cells, with proliferative cells being the main targets, suggesting the gut as an HEV reservoir.

bioRxiv · Mar 27, 2024Microbiology

A SCID mouse model to evaluate the efficacy of antivirals against SARS-CoV-2 infection

R. Abdelnabi, C. S. Foo, S. Kaptein, R. Boudewijns, L. Vangeel, S. De Jonghe, D. Jochmans, B. Weynand, J. Neyts

This paper establishes a SCID mouse model infected with the SARS-CoV-2 beta B.1.351 variant to evaluate antiviral efficacy, showing significant reduction in viral load with Molnupiravir and Nirmatrelvir.

bioRxiv · May 13, 2022Microbiology

Perturbation of alphavirus and flavivirus infectivity by components of the bacterial cell wall

L. Langendries, S. Jacobs, R. Abdelnabi, S. Verwimp, S. Kaptein, P. Baatsen, L. Van Mellaert, L. Delang

This study shows that bacterial cell wall components reduce alphavirus and flavivirus infectivity by directly interacting with viral particles in vitro.

bioRxiv · May 7, 2021Microbiology