Author

A. Sebastian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 2 Physiology· 2 Animal Behavior & Cognition· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 8 Approach:experimental assay· 8 Organism:mouse· 8 Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

I. Albert· 5 shared S. E. Lindner· 3 shared K. T. Rios· 2 shared A. M. Phillips· 1 shared A. Rasley· 1 shared B. Chicana· 1 shared B. J. Power· 1 shared C. Donham· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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5 shared papersMicrobiology

I. Albert

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Global Release of Translational Repression Across Plasmodiums Host-to-Vector Transmission Event

K. T. Rios, J. P. McGee, A. Sebastian, R. L. Moritz, M. Feric, S. Absalon, K. E. Swearingen, S. E. Lindner

This study identifies the global release of translational repression in Plasmodium parasites during host-to-vector transmission using transcriptomics and proteomics.

bioRxiv · Feb 1, 2024 · PreprintMicrobiology

Vhl deletion in Dmp1-expressing cells alters MEP metabolism and promotes stress erythropoiesis

J. M. Emery, B. Chicana, H. Taglinao, C. Ponce, C. Donham, H. Padmore, A. Sebastian, S. L. Trasti, J. O. Manilay

This study shows that deleting Vhl in Dmp1-expressing cells increases stress erythropoiesis by altering MEP metabolism and inducing hypoxia-like responses.

bioRxiv · Jul 25, 2023Physiology

Long-Read Genome Assembly and Gene Model Annotations for the Rodent Malaria Parasite Plasmodium yoelii 17XNL

M. J. Godin, A. Sebastian, I. Albert, S. E. Lindner

This paper presents a high-quality genome assembly and gene models for Plasmodium yoelii 17XNL using long-read sequencing, revealing differences from the 17X strain.

bioRxiv · Jan 6, 2023 · PreprintMicrobiology

MAVS mediates a protective immune response in the brain to Rift Valley fever virus

D. R. Weilhammer, N. R. Hum, F. A. Bourguet, A. Sebastian, D. Lam, A. M. Phillips, K. R. Sanchez, A. Rasley, G. G. Loots

This study shows that MAVS is critical for microglial antiviral responses in the brain during RVFV infection, reducing viral burden and mortality.

bioRxiv · Dec 22, 2021Immunology

The Plasmodium NOT1-G Paralogue Acts as an Essential Nexus for Sexual Stage Maturation and Parasite Transmission

K. J. Hart, B. J. Power, K. T. Rios, A. Sebastian, S. E. Lindner

This study identifies PyNOT1-G as essential for Plasmodium sexual stage maturation and transmission, showing its role in mRNA homeostasis and gametogenesis.

bioRxiv · May 25, 2021Microbiology

Effect of Adolescent Stress on Adult Morphine-Induced Behavioral Sensitization is Dependent Upon Genetic Background

H. Kamens, C. Miller, J. Caulfield, D. Zeid, W. Horton, C. Silva, A. Sebastian, I. Albert, T. Gould, D. Fishbein, P. S. Grigson, S. Cavigelli

This study investigates how adolescent stress affects adult morphine behavior, finding genetic differences in how C57BL/6J and BALB/cJ mice respond to stress and morphine.

bioRxiv · Jan 20, 2021 · PreprintAnimal Behavior & Cognition

RNAseq studies reveal distinct transcriptional response to vitamin A deficiency in small intestine versus colon, uncovering novel vitamin A-regulated genes

Z. Chai, Y. Lyu, Q. Chen, C.-H. Wei, L. M. Snyder, V. Weaver, A. Sebastian, I. Albert, Q. Li, M. Cantorna, C. Ross

This study compares gene expression in the small intestine and colon of vitamin A deficient mice, identifying distinct transcriptional responses and novel VA-regulated genes.

bioRxiv · May 19, 2020Physiology

Artificial selection finds new hypotheses for the mechanism of Wolbachia-mediated dengue blocking in mosquitoes

S. A. Ford, I. Albert, S. L. Allen, S. Chenoweth, M. Jones, C. Koh, A. Sebastian, L. T. Sigle, E. A. McGraw

The paper uses artificial selection to identify genetic variations linked to Wolbachia-mediated dengue blocking in mosquitoes and proposes hypotheses about the underlying mechanisms.

bioRxiv · Nov 25, 2019Evolutionary Biology

Real-time in vivo Global Transcriptional Dynamics During Plasmodium falciparum Blood-stage Development

H. J. Painter, N. C. Chung, A. Sebastian, I. Albert, J. D. Storey, M. Llinas

This study uses 4-TU labeling to track real-time transcription dynamics of Plasmodium falciparum during its blood-stage development, revealing transcription timing and stabilization patterns across the IDC.

bioRxiv · Feb 14, 2018Microbiology

Comprehensive profiling of TCRβ repertoire in a non-model species (the bank vole) using high-throughput sequencing

M. Migalska, A. Sebastian, J. Radwan

This study profiles the TCRβ repertoire in bank voles using HTS, identifying V and J genes and quantifying clonotype diversity.

bioRxiv · Dec 26, 2017Immunology