Author

S. L. Bridges

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

M. I. Danila· 2 shared A. Aggarwal· 1 shared A. Cesano· 1 shared A. Mahendra· 1 shared A. Nellore· 1 shared A. Rosal-Vela· 1 shared A. Rosenberg· 1 shared B. Diamond· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

M. I. Danila

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Author profile →

3 papers

Recent·Most cited

A Systems Immunology Approach Identifies Cytokine-Induced STAT Signaling Pathways Critical to Rheumatoid Arthritis Disease Activity and Treatment Response

S. L. Bridges, J. Ptacek, R. E. Hawtin, D. Sun, B. Louie, E. Evensen, B. Mittleman, A. Cesano, G. Cavet, C. O. Bingham, S. S. Cofield, J. R. Curtis, M. I. Danila, C. Raman, R. Furie, , P. K. Gregersen

bioRxiv · Jul 8, 2019 · PreprintImmunology

IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation

E. Zumaquero, S. L. Stone, C. D. Scharer, S. A. Jenks, A. Nellore, B. Mousseau, A. Rosal-Vela, D. Botta, J. E. Bradley, W. Wojciechowski, T. Ptacek, M. I. Danila, J. C. Edberg, S. L. Bridges, R. P. Kimberly, , F. E. Lund

This study shows IFNγ promotes T-bet expressing B cell differentiation and epigenetic reprogramming in humans, enhancing IL-21-driven antibody production.

bioRxiv · Feb 21, 2019Immunology

Beyond Autoantibodies: Biological Roles Of Human Autoreactive B Cells In Rheumatoid Arthritis Revealed By Whole Transcriptome Profiling

A. Mahendra, X. Yang, S. Abnouf, D. Park, S. Soomro, J. R. T. Adolacion, J. Roszik, C. Coarfa, G. Romain, K. Wanzeck, S. L. Bridges, A. Aggarwal, P. Qiu, S. K. Agarwal, C. Mohan, N. Varadarajan

This study identifies novel roles of autoreactive B cells in RA through transcriptome profiling, revealing potential therapeutic targets and mechanisms.

bioRxiv · Jun 1, 2017Immunology