Author

S. L. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. H. Wong· 2 shared J. H.-M. Tong· 2 shared K.-F. To· 2 shared Y. Chen· 2 shared C. H. Li· 1 shared E. S. K. Ma· 1 shared H. Valantine· 1 shared J. Wong· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

C. H. Wong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

W. Gai, Z. Zhou, S. Agbor-Enoh, X. Fan, S. Lian, P. Jiang, S. H. Cheng, J. Wong, S. L. Chan, M. K. Jang, Y. Yang, R. H. S. Liang, W. K. Chan, E. S. K. Ma, T. Y. Leung, , Y. M. D. Lo

This paper introduces GETMap, a method to determine tissue origin of plasma DNA carrying genetic variants, validated across prenatal testing, transplantation, and oncology scenarios.

bioRxiv · Nov 13, 2020Physiology

Ectopic HOTTIP Expression Induces Non-canonical Transactivation Pathways to Promote Growth and Invasiveness in Pancreatic Ductal Adenocarcinoma

C. H. Wong, C. H. Li, Q. He, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies HOTTIP's role in promoting pancreatic ductal adenocarcinoma through both canonical HOXA13-mediated and non-canonical WDR5-MLL1-H3K4me3 pathways.

bioRxiv · Oct 21, 2019Cancer Biology

CircFOXK2 Promotes Tumor Growth and Metastasis of Pancreatic Ductal Adenocarcinoma via Complexing with RNA Binding Proteins and Sponging MiR-942

C. H. Wong, U. K. Lou, Y. Li, S. L. Chan, J. H.-M. Tong, K.-F. To, Y. Chen

This study identifies circFOXK2 as an oncogenic circRNA in PDAC that promotes tumor growth and metastasis by acting as a miR-942 sponge and interacting with RNA-binding proteins.

bioRxiv · Oct 3, 2019Cancer Biology