Author

W. K. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Bolado Carrancio· 1 shared A. Deorukhkar· 1 shared A. J. Grossberg· 1 shared A. P. Jarman· 1 shared A. von Kriegsheim· 1 shared C. Taniguchi· 1 shared E. L. G. Samuel· 1 shared E. S. K. Ma· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Bolado Carrancio

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prdm1 Positively Regulates Liver Group 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity

J. He, L. Gao, P. Wang, W. K. Chan, Y. Zheng, Y. Zhang, J. Sun, X. Li, J. Wang, X. Li, H. Chen, Z. Yang, Y. Wang

This study shows Prdm1 regulates liver cNK cells and ILC1s, affecting cancer metastasis and immune communication, with implications for liver cancer immunotherapy.

bioRxiv · Oct 20, 2023Immunology

The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly

P. zur Lage, Z. Xi, J. Lennon, I. Hunter, W. K. Chan, A. Bolado Carrancio, A. von Kriegsheim, A. P. Jarman

This study identifies Dnaaf3 as essential for axonemal dynein assembly in Drosophila, leading to defects in mechanosensory and reproductive functions.

bioRxiv · May 11, 2021Cell Biology

Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology

W. Gai, Z. Zhou, S. Agbor-Enoh, X. Fan, S. Lian, P. Jiang, S. H. Cheng, J. Wong, S. L. Chan, M. K. Jang, Y. Yang, R. H. S. Liang, W. K. Chan, E. S. K. Ma, T. Y. Leung, , Y. M. D. Lo

This paper introduces GETMap, a method to determine tissue origin of plasma DNA carrying genetic variants, validated across prenatal testing, transplantation, and oncology scenarios.

bioRxiv · Nov 13, 2020Physiology

Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

J. M. Molkentine, T. N. Fujimoto, T. Horvath, A. J. Grossberg, A. Deorukhkar, E. L. G. Samuel, W. K. Chan, P. L. Lorenzi, R. Dantzer, J. M. Tour, K. A. Mason, C. Taniguchi

This study shows oral WR-2721 provides effective radioprotection and survival benefits after lethal radiation by selectively protecting the intestine.

bioRxiv · Mar 27, 2018Cancer Biology