Author

S. M. Ardell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

J. J. Lee· 1 shared J. M. Borin· 1 shared J. R. Meyer· 1 shared K. D. Corbett· 1 shared K. R. Gerbino· 1 shared S. Kryazhimskiy· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperEvolutionary Biology

J. J. Lee

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2 papers

Recent·Most cited

Bacteriophage {Phi}21s receptor-binding protein evolves new functions through destabilizing mutations that generate non-genetic phenotypic heterogeneity

K. R. Gerbino, J. M. Borin, S. M. Ardell, J. J. Lee, K. D. Corbett, J. R. Meyer

This study shows that bacteriophage Φ21 evolves new host receptor usage through destabilizing mutations that create non-genetic phenotypic heterogeneity in viral particles.

bioRxiv · Apr 15, 2024Evolutionary Biology

The Population Genetics of Collateral Resistance and Sensitivity

S. M. Ardell, S. Kryazhimskiy

The paper shows resistance mutations in E. coli have diverse collateral effects and proposes a method to predict and robustly rank drug pairs to minimize collateral resistance risk.

bioRxiv · Aug 25, 2020Evolutionary Biology