Author

S. M. Brewer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. M. Monack· 2 shared J. A. Klein· 1 shared J. A. McKenna· 1 shared J. D. Honeycutt· 1 shared J. G. Vilches-Moure· 1 shared K. E. Bernstein· 1 shared L. Moura Massis· 1 shared M. d. M. Margalef-Catala· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

D. M. Monack

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2 papers

Recent·Most cited

Single-cell profiling identifies ACE+ granuloma macrophages as a non-permissive niche for intracellular bacteria during persistent Salmonella infection

T. H. M. Pham, Y. Xue, S. M. Brewer, K. E. Bernstein, S. R. Quake, D. M. Monack

The paper identifies ACE+ granuloma macrophages as non-permissive for intracellular Salmonella persistence using single-cell transcriptomics in mice.

bioRxiv · Jul 21, 2022Immunology

Gut regulatory T cells mediate immunological tolerance in Salmonella Typhimurium-infected superspreader hosts by suppressing cytotoxic activity of T cells.

L. Moura Massis, S. Ruddle, S. M. Brewer, R. Schade, R. Narasimhan, J. D. Honeycutt, T. H. Pham, J. A. McKenna, S. W. Brubaker, P. Chairatana, J. A. Klein, M. d. M. Margalef-Catala, M. R. Amieva, J. G. Vilches-Moure, D. M. Monack

The paper identifies regulatory T cells (Tregs) as critical for maintaining immunological tolerance in superspreader hosts infected with Salmonella Typhimurium by suppressing cytotoxic T-cell activity.

bioRxiv · Jul 16, 2021 · PreprintImmunology