Author

S. M. Golomb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Q. Wang· 3 shared S. Zhang· 3 shared B. Palakurthi· 2 shared I. H. Guldner· 2 shared A. K. Martino· 1 shared A. Zhao· 1 shared E. Howe· 1 shared I. M. Guldner· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Q. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Maximizing the Anti-tumor Potential of Immune Checkpoint Blockade through Modulation of Myeloid-specific CXCL16 and STAT1 Signaling

B. Palakurthi, I. H. Guldner, X. Liu, A. K. Martino, Q. Wang, S. Fross, R. A. Neff, S. M. Golomb, E. Howe, S. Zhang

This study shows that modulating STAT1 signaling in chemotherapy-primed breast cancer enhances anti-PD-1 immunotherapy efficacy by altering myeloid cell dynamics.

bioRxiv · Mar 28, 2022 · PreprintCancer Biology

Multi-modal single cell analysis reveals brain immune landscape plasticity during aging and gut microbiota dysbiosis

S. M. Golomb, I. H. Guldner, A. Zhao, Q. Wang, B. Palakurthi, J. Lopez, K. Yang, S. Zhang

This study uses CITE-seq to analyze brain immune cell plasticity in aged mice with and without gut dysbiosis, revealing transcriptional shifts in monocytes and ILCs linked to neuroinflammation.

bioRxiv · Jul 15, 2020Immunology

Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor resistant HER2-positive breast cancer

Q. Wang, I. M. Guldner, S. M. Golomb, L. Sun, J. Harris, X. Lu, S. Zhang

This study uses single-cell profiling to identify immunosuppressive cells in CDK4/6 inhibitor-resistant HER2+ breast cancer and shows that combinatorial immunotherapy can overcome resistance.

bioRxiv · Jun 14, 2019Cancer Biology