Author

S. M. Lam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

G. Shui· 3 shared A. Yavuz· 1 shared B. Zhang· 1 shared C. Lu· 1 shared C. Zhang· 1 shared C. Zhao· 1 shared C.-S. Zhang· 1 shared H. Zhou· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPhysiology

G. Shui

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lithocholic acid phenocopies rejuvenating and life-extending effects of calorie restriction

Q. Qu, Y. Chen, Y. Wang, S. Long, W. Wang, H.-Y. Yang, M. Li, X. Tian, X. Wei, Y.-H. Liu, S. Xu, C. Zhang, M. Zhu, S. M. Lam, J. Wu, , S.-C. Lin

This study identifies lithocholic acid as a metabolite that mimics calorie restriction's anti-aging effects in multiple species through AMPK activation.

bioRxiv · Dec 7, 2023 · PreprintPhysiology

Target lipidomics reveals associations between serum sphingolipids and insulin sensitivity by the glucose clamp

J. Ye, X. Ye, W. Jiang, C. Lu, X. Geng, C. Zhao, Y. Ma, P. Yang, S. M. Lam, G. Shui, T. Yang, J. Z. Li, Y. Gong, Z. Fu, H. Zhou

This study identifies serum sphingolipids associated with insulin sensitivity using lipidomics and glucose clamp techniques, finding SM/Cer and SM d18:0/26:0 as potential biomarkers.

bioRxiv · Oct 23, 2020Physiology

Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration

L. Yang, J. Liang, S. M. Lam, A. Yavuz, M. C. Wang, G. Shui, M. Ding, X. Huang

This study shows that neuronal lipolysis prevents lipid droplet accumulation and alleviates neurodegeneration in C. elegans by regulating PUFA partitioning and phospholipid incorporation.

bioRxiv · Feb 13, 2020Cell Biology