Author

M. J. McElrath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 8

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 8 Organism:human· 8 Research Focus:differential expression· 7 Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Research Focus:cell-cell communication· 4 Assay:proteomics· 4 Assay:scRNA-seq· 4

Frequent Co-Authors

K. W. Cohen· 4 shared E. W. Newell· 3 shared S. C. De Rosa· 3 shared A. Talla· 2 shared C. N. Levy· 2 shared E. M. Coffey· 2 shared F. Calienes· 2 shared F. Hladik· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

K. W. Cohen

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Author profile →

8 papers

Recent·Most cited

Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge

D. A. Oyong, F. J. Duffy, M. L. Neal, Y. Du, J. Carnes, K. V. Schwedhelm, N. Hertoghs, S.-H. Jun, H. Miller, J. D. Aitchison, S. C. De Rosa, E. W. Newell, M. J. McElrath, S. M. McDermott, K. D. Stuart

The paper identifies distinct immune responses associated with vaccination status and protection outcomes after malaria challenge using transcriptome and cellular profiling.

bioRxiv · Dec 9, 2022 · PreprintImmunology

Persistent serum protein signatures define an inflammatory subset of long COVID

A. Talla, S. V. Vasaikar, G. Szeto, M. P. Lemos, J. L. Czartoski, H. MacMillan, Z. Moodie, K. W. Cohen, L. B. Fleming, Z. Thomson, L. Okada, L. A. Becker, E. M. Coffey, S. C. DeRosa, E. W. Newell, , T. R. Torgerson

Serum proteome profiling identifies subsets of long COVID patients with evidence of persistent inflammation and key immune signaling pathways.

bioRxiv · May 9, 2022 · PreprintImmunology

Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain

M. D. Gray, J. Feng, C. E. Weidle, K. W. Cohen, L. Ballweber-Fleming, A. J. MacCamy, C. N. Huynh, J. J. Trichka, D. Montefiori, G. Ferrari, M. Pancera, M. J. McElrath, L. Stamatatos

The paper identifies an antibody from a clinical trial that binds a different HIV-1 Env domain than VRC01-class antibodies and shows that epitope switching requires specific CDR changes.

bioRxiv · Aug 21, 2021Immunology

Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity

Y. Du, N. Hertoghs, J. Carnes, S. M. McDermott, M. L. Neal, K. V. Schwedhelm, M. J. McElrath, S. C. De Rosa, J. D. Aitchison, K. D. Stuart

The paper analyzes immune responses to malaria vaccination and finds that excessive early inflammation correlates with impaired immunity.

bioRxiv · Jul 28, 2021Immunology

T helper 2 transcriptional profile predicts single-cell HIV envelope-specific polyfunctional CD4+ T cells correlated with reduced risk of infection in RV144 trial

K. W. Cohen, Y. Tian, C. Thayer, A. Seese, R. Amezquita, M. J. McElrath, S. De Rosa, R. Gottardo

bioRxiv · Jun 7, 2021 · PreprintImmunology

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence

A. Talla, S. V. Vasaikar, M. P. Lemos, Z. Moodie, M.-P. L. Pebworth, K. E. Henderson, K. W. Cohen, J. L. Czartoski, L. Lai, M. S. Suthar, A. T. Heubeck, P. C. Genge, C. R. Roll, M. Weiss, J. Reading, , T. F. Bumol

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

bioRxiv · May 26, 2021 · PreprintImmunology

Treatment with commonly used antiretroviral drugs induces a type I/III interferon signature in the gut in the absence of HIV infection

S. M. Hughes, C. N. Levy, F. Calienes, J. D. Stekler, U. Pandey, L. Vojtech, A. R. Berard, K. Birse, L. Noel-Romas, B. Richardson, J. B. Golden, M. Cartwright, A. C. Collier, C. E. Stevens, M. E. Curlin, , F. Hladik

This study shows that oral TDF/FTC antiretroviral drugs induce a type I/III interferon signature in the gut without HIV infection, potentially affecting immune responses.

bioRxiv · Aug 3, 2020Immunology

Cryopreservation of human mucosal tissues

S. M. Hughes, A. L. Ferre, S. E. Yandura, C. Shetler, C. A. R. Baker, F. Calienes, C. N. Levy, R. D. Astronomo, Z. Shu, G. M. Lentz, M. Fialkow, A. C. Kirby, M. J. McElrath, E. Sinclair, L. C. Rohan, , F. Hladik

This study compares cryopreservation and vitrification protocols for human mucosal tissues, finding cryopreservation effective for cervicovaginal tissues but less so for colorectal tissues.

bioRxiv · May 30, 2018Immunology