Author

S. M. Richardson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Swift· 4 shared H. T. Gilbert· 3 shared O. Dobre· 3 shared V. Mallikarjun· 3 shared J. Llewellyn· 2 shared M. R. Jackson· 2 shared A. Galarza Torre· 1 shared A. P. Gilmore· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCell Biology

J. Swift

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Author profile →

4 papers

Recent·Most cited

Loss of cytoskeletal proteostasis links dysregulation of cell size and mechanotransduction in mesenchymal stem cell senescence

V. Mallikarjun, O. Dobre, M. R. Jackson, M. Kidd, J. Llewellyn, H. T. Gilbert, S. M. Richardson, J. Swift

This study shows that loss of cytoskeletal proteostasis in senescent mesenchymal stem cells disrupts mechanotransduction and matrix protein secretion, linking cell size dysregulation to tissue maintenance issues.

bioRxiv · Oct 9, 2022 · PreprintCell Biology

Senescence inhibits the chaperone response to thermal stress

J. Llewellyn, V. Mallikarjun, E. Appleton, M. Osipova, H. T. Gilbert, S. M. Richardson, S. J. Hubbard, J. Swift

The paper shows that senescence impairs the chaperone response to thermal stress in human mesenchymal stem cells, leading to misfolded protein accumulation.

bioRxiv · Jun 15, 2021 · PreprintCell Biology

Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading

H. T. Gilbert, V. Mallikarjun, O. Dobre, M. R. Jackson, R. Pedley, A. P. Gilmore, S. M. Richardson, J. Swift

The paper investigates how human mesenchymal stem cells respond to mechanical loading by decoupling nuclear and cytoskeletal mechano-transmission at the protein level.

bioRxiv · May 9, 2018Biophysics

An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness

A. Galarza Torre, J. E. Shaw, A. Wood, H. T. J. Gilbert, O. Dobre, P. Genever, K. Brennan, S. M. Richardson, J. Swift

The paper shows that an immortalized mesenchymal stem cell line retains mechano-responsiveness and can serve as a reporter for substrate stiffness.

bioRxiv · Feb 21, 2018Bioengineering