Author

M. R. Jackson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Chalmers· 2 shared H. T. Gilbert· 2 shared J. Swift· 2 shared M. K. MacLeod· 2 shared O. Dobre· 2 shared S. K. Chahal· 2 shared S. M. Richardson· 2 shared V. Mallikarjun· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. J. Chalmers

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ClonoScreen3D: a novel three-dimensional clonogenic screening platform for identification of radiosensitizers for glioblastoma

M. R. Jackson, A. R. Richards, A.-B. A. Oladipupo, S. K. Chahal, S. Caragher, A. J. Chalmers, N. Gomez-Roman

ClonoScreen3D is a 3D clonogenic screening platform that identifies radiosensitizers for glioblastoma by testing drug-radiation interactions using patient-derived cell lines.

International Journal of Radiation Oncology*Biology*Physics · Sep 1, 2024Peer-reviewedCancer Biology

Enhanced survival and low proliferation marks multifunctional virus specific memory CD4 T cells

L. M. Westerhof, J. Noonan, K. E. Hargrave, E. T. Chimbayo, Z. Cheng, T. Purnell, M. R. Jackson, N. Borcherding, M. K. MacLeod

The paper identifies multifunctional virus-specific memory CD4 T cells that exhibit enhanced survival and low proliferation, suggesting survival, not proliferation, drives their persistence in the memory pool.

bioRxiv · Dec 13, 2022 · PreprintImmunology

Loss of cytoskeletal proteostasis links dysregulation of cell size and mechanotransduction in mesenchymal stem cell senescence

V. Mallikarjun, O. Dobre, M. R. Jackson, M. Kidd, J. Llewellyn, H. T. Gilbert, S. M. Richardson, J. Swift

This study shows that loss of cytoskeletal proteostasis in senescent mesenchymal stem cells disrupts mechanotransduction and matrix protein secretion, linking cell size dysregulation to tissue maintenance issues.

bioRxiv · Oct 9, 2022 · PreprintCell Biology

Low-dose lung radiotherapy for COVID-19 lung disease: a pre-clinical efficacy study in a bleomycin model of pneumonitis.

M. R. Jackson, K. Stevenson, S. K. Chahal, E. Curley, G. Finney, R. Gutierrez-Quintana, E. Onwubiko, A. F. Rupp, K. Strathdee, M. K. MacLeod, C. McSharry, A. J. Chalmers

This study evaluates low-dose lung radiotherapy (LDLR) in a bleomycin pneumonitis model, finding that 1.0 Gy LDLR improves recovery and reduces inflammation, particularly in moderate cases.

bioRxiv · Mar 3, 2021Immunology

Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading

H. T. Gilbert, V. Mallikarjun, O. Dobre, M. R. Jackson, R. Pedley, A. P. Gilmore, S. M. Richardson, J. Swift

The paper investigates how human mesenchymal stem cells respond to mechanical loading by decoupling nuclear and cytoskeletal mechano-transmission at the protein level.

bioRxiv · May 9, 2018Biophysics