Author

S. Mansoor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Plant Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Assay:protein structure· 3 Approach:experimental assay· 2 Organism:plant (other)· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Baek· 3 shared D. Baker· 2 shared I. Amin· 2 shared A. A. Khan· 1 shared A. Amin· 1 shared A. Cakir· 1 shared A. Faiq· 1 shared A. G. O. Demir· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiochemistry

M. Baek

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Comparative Analysis, Diversification and Functional Validation of Plant Nucleotide-Binding Site Domain Genes

A. Hussain, A. A. Khan, M. Q. Aslam, A. Nazar, N. Zaman, A. Amin, M. A. Mahmood, M. S. Mukhtar, H. U. U. Rahman, M. Farooq, M. Saeed, I. Amin, S. Mansoor

This study identifies and classifies NBS domain genes across 34 plant species, revealing structural diversity and functional roles in plant-pathogen interactions.

bioRxiv · Aug 9, 2023Plant Biology

Protein Ensemble Generation through VariationalAutoencoder Latent Space Sampling

S. Mansoor, M. Baek, H. Park, G. R. Lee, D. Baker

The paper generates high-quality protein conformations using a variational autoencoder, achieving better sampling accuracy than MD simulations or AlphaFold2 for K-Ras.

bioRxiv · Aug 1, 2023Biochemistry

Accurate Mutation Effect Prediction using RoseTTAFold

S. Mansoor, M. Baek, D. Juergens, J. L. Watson, D. Baker

This study evaluates RoseTTAFold's ability to predict mutation effects without additional training, achieving state-of-the-art accuracy across diverse protein families.

bioRxiv · Nov 4, 2022 · PreprintBiochemistry

Hexokinase 1b is a novel target for non-small-cell lung cancer

Y. Yozgat, E. Karakoc, O. Sahin, S. Cimen, W. M. Rabeh, M. S. Aydin, A. Mardinoglu, I. Gursel, A. Cakir, O. Sensoy, E. M. Ozdemir, Y. Bayrak, M. Z. Gunluoglu, O. Saatci, J. Jabbar, , M. A. Cevher

This study identifies HK1b as a novel therapeutic target in NSCLC by showing its role in glycolysis, tumor progression, and cisplatin resistance.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

Fully Transient CRISPR/Cas12f system in plants capable of broad-spectrum resistance against Begomovirus

S. Haider, A. Faiq, M. Z. Khan, S. Mansoor, I. Amin

The paper develops a transient CRISPR/Cas12f system in plants that provides broad-spectrum resistance against Begomoviruses with high efficiency and reduced off-target effects.

bioRxiv · Jun 7, 2022 · PreprintPlant Biology

Toward More General Embeddings for Protein Design: Harnessing Joint Representations of Sequence and Structure

S. Mansoor, M. Baek, U. Madan, E. Horvitz

This paper introduces a data-efficient method for protein embeddings by jointly training on sequence and structure, improving mutation effect prediction through enriched representations.

bioRxiv · Sep 1, 2021 · PreprintBiochemistry