M. S. Mukhtar

Negative Synergistic Effects of Drought and Heat During Flowering and Seed Setting in Soybean

This study examines the combined effects of drought and heat on soybean physiology, yield, and gene expression during flowering and seed setting, finding that combined stress has more severe negative impacts than individual stresses.

Co-occurrence Networks and Topological Analyses Revealed Microbiome Structures in Soybean Roots from a Louisiana Soybean Field Severely Damaged by Prolonged High Temperatures and Drought Stress

The paper analyzes microbial communities in soybean roots under drought stress, finding distinct endophytic bacterial structures between surviving and non-surviving plants.

Single nuclei multiomics reveals the drought-driven gene regulatory atlas in Arabidopsis

This study uses single-nucleus multiomics to uncover drought-driven gene regulatory mechanisms in Arabidopsis, identifying cell type-specific markers and regulatory networks.

Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing.

This study uses single-cell RNA sequencing to reveal molecular heterogeneity in quiescent melanocyte stem cells and identifies novel subpopulations with distinct immune privilege and differentiation potential.

NK and NKT cells in the pathogenesis of Hidradenitis suppurativa: Novel therapeutic strategy through targeting of CD2

This study identifies expanded NKT and NK cells with elevated CD2 in HS lesions and shows CD2 blockade reduces inflammation and fibrosis.

Comparative Analysis, Diversification and Functional Validation of Plant Nucleotide-Binding Site Domain Genes

This study identifies and classifies NBS domain genes across 34 plant species, revealing structural diversity and functional roles in plant-pathogen interactions.

Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

This study establishes mouse models of Cdk5-driven Medullary Thyroid Carcinoma (MTC) that recapitulate human tumor aggressiveness and identifies metabolic pathway perturbations as critical for aggressive growth.

Dysregulated Protein Translation Control in Hidradenitis Suppurativa: Implication for Lesion-associated Squamous Cell Carcinoma Development

This study identifies dysregulated eIF4F translation initiation complex in HS lesions, linking it to SCC development through Cyclin D1 and c-Myc overexpression.

Ex Vivo Culture Models of Hidradenitis Suppurativa for defining molecular pathogenesis and treatment efficacy of novel drugs

This paper develops three ex vivo skin culture models for HS to study molecular pathogenesis and drug efficacy.

Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

This paper develops a mouse model of PanNETs driven by Cdk5 and shows its relevance to human tumors, supporting Cdk5 as a therapeutic target.

EffectorK, a comprehensive resource to mine for pathogen effector targets in the Arabidopsis proteome

The paper constructs an interactomic network of Arabidopsis proteins and pathogen effectors and develops EffectorK, a database to explore these interactions.

Phosphoprotein-based Biomarkers as Predictors for Cancer Therapy

The paper identifies phosphoprotein biomarkers for Cdk5 activity in neuroendocrine tumors and shows their predictive value for anti-Cdk5 therapy.