Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity
S. Belhimeur, S. Briquet, R. Peronet, J. Pham, P.-H. Commere, P. Formaglio, R. Amino, A. Scherf, O. Silvie, S. MECHERI
This study shows that Plasmodium parasites engineered to express murine IL-6 fail to progress to blood stage infection and induce long-lasting CD8+ T cell-mediated immunity.
bioRxiv · Nov 16, 2021Immunology