Author

S. Metcalf

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A.-M. Baker· 1 shared E. Lakatos· 1 shared F. Nicolini· 1 shared H. Hockings· 1 shared K. Smith· 1 shared M. A. Khan· 1 shared M. Lockley· 1 shared M. Mossner· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A.-M. Baker

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1 paper

Recent·Most cited

Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer

H. Hockings, E. Lakatos, W. Huang, M. Mossner, M. A. Khan, S. Metcalf, F. Nicolini, K. Smith, A.-M. Baker, T. Graham, M. Lockley

This study demonstrates that adaptive therapy reduces chemotherapy resistance in ovarian cancer by exploiting fitness costs of resistant cells, extending survival in mice and correlating with disease burden in patients.

bioRxiv · Jul 21, 2023 · PreprintCancer Biology