Author

H. Hockings

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Nicolini· 2 shared M. Lockley· 2 shared W. Huang· 2 shared A.-M. Baker· 1 shared E. Lakatos· 1 shared E. Maniati· 1 shared G. E. Wood· 1 shared H. B. Mirza· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

F. Nicolini

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2 papers

Recent·Most cited

Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer

H. Hockings, E. Lakatos, W. Huang, M. Mossner, M. A. Khan, S. Metcalf, F. Nicolini, K. Smith, A.-M. Baker, T. Graham, M. Lockley

This study demonstrates that adaptive therapy reduces chemotherapy resistance in ovarian cancer by exploiting fitness costs of resistant cells, extending survival in mice and correlating with disease burden in patients.

bioRxiv · Jul 21, 2023 · PreprintCancer Biology

Platinum resistance induces diverse evolutionary trajectories in high grade serous ovarian cancer

J. I. Hoare, H. Hockings, J. Saxena, V. L. Silva, E. Maniati, H. B. Mirza, W. Huang, G. E. Wood, F. Nicolini, T. A. Graham, I. A. McNeish, M. Lockley

This study investigates platinum resistance in high grade serous ovarian cancer by analyzing transcriptomic features and evolutionary trajectories in resistant models.

bioRxiv · Jul 23, 2020 · PreprintCancer Biology