Author

S. N. Spector

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Organism:human· 1

Frequent Co-Authors

K. A. Stapleford· 4 shared S. A. Thannickal· 3 shared M. G. Noval· 2 shared B. A. Rodriguez-Rodriguez· 1 shared C. Loomis· 1 shared D. E. Alvarez· 1 shared E. Bartnicki· 1 shared F. Izzo· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersMicrobiology

K. A. Stapleford

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4 papers

Recent·Most cited

La Crosse virus reassortants highlight genomic determinants of infection and pathogenesis

N. C. Rondeau, S. N. Spector, S. A. Thannickal, K. A. Stapleford

This study uses genomic reassortment to identify how different segments of La Crosse virus affect infection and pathogenesis in vitro and in vivo.

bioRxiv · Mar 11, 2024 · PreprintMicrobiology

The chikungunya virus E1 glycoprotein fusion loop and hinge alter glycoprotein dynamics leading to cell and host specific changes in infectivity.

S. A. Thannickal, L. Battini, S. N. Spector, M. G. Noval, D. E. Alvarez, K. A. Stapleford

This study investigates how mutations in the CHIKV E1 glycoprotein's fusion loop and hinge affect virus infectivity in different cell types and hosts by altering E1-E2 dynamics.

bioRxiv · Nov 3, 2023 · PreprintMicrobiology

The La Crosse virus class II fusion glycoprotein ij loop contributes to infectivity and cholesterol-dependent entry.

S. A. Thannickal, S. N. Spector, K. A. Stapleford

This study investigates the role of the La Crosse virus (LACV) class II fusion glycoprotein ij loop in infectivity and cholesterol-dependent entry, showing that specific residues are critical for virus function.

bioRxiv · Feb 22, 2023 · PreprintMicrobiology

MAVS signaling is required for clearance of chikungunya heart infection and prevention of chronic inflammation in vascular tissue

M. G. Noval, S. N. Spector, E. Bartnicki, F. Izzo, N. Narula, S. T. Yeung, P. Damani-Yokota, M. Z. Dewan, V. Mezzano, B. A. Rodriguez-Rodriguez, C. Loomis, K. M. Khanna, K. A. Stapleford

This study investigates CHIKV-induced heart disease using mouse models and human cells, showing MAVS signaling is critical for viral clearance and preventing chronic vascular inflammation.

bioRxiv · May 27, 2022 · PreprintMicrobiology