Author

V. Mezzano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Loomis· 3 shared A. Tsirigos· 2 shared E. Bartnicki· 2 shared K. M. Khanna· 2 shared A. A. S. Shadaloey· 1 shared A. H. Yeaton· 1 shared A. Herrera· 1 shared A. J. Bhutkar· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

C. Loomis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MetFinder: a neural network-based tool for automated quantitation of metastatic burden in histological sections from animal models

A. Karz, N. Coudray, E. Bayraktar, K. Galbraith, G. Jour, A. A. S. Shadaloey, N. Eskow, A. Rubanov, M. Navarro, R. Moubarak, G. Baptiste, G. Levinson, V. Mezzano, M. Alu, C. Loomis, , E. Hernando

MetFinder uses a deep neural network to automate metastasis burden quantification in histological sections from mouse models, improving throughput and resolution compared to current methods.

bioRxiv · Sep 7, 2023 · PreprintCancer Biology

Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

A. Rashidfarrokhi, R. Pillai, Y. Hao, W. Wu, B. Karadal-Ferrena, S. G. dimitriadoy, M. Cross, A. H. Yeaton, S. Ming Huang, A. J. Bhutkar, A. Herrera, S. Rajalingam, M. Hayashi, K.-l. Huang, E. Bartnicki, , T. Papagiannakopoulos

This study identifies a LKB1-LIF signaling axis in tumors that promotes immune evasion by reprogramming myeloid cells, and shows that inhibiting LIF signaling reduces tumor growth.

bioRxiv · Jul 15, 2023 · PreprintCancer Biology

MAVS signaling is required for clearance of chikungunya heart infection and prevention of chronic inflammation in vascular tissue

M. G. Noval, S. N. Spector, E. Bartnicki, F. Izzo, N. Narula, S. T. Yeung, P. Damani-Yokota, M. Z. Dewan, V. Mezzano, B. A. Rodriguez-Rodriguez, C. Loomis, K. M. Khanna, K. A. Stapleford

This study investigates CHIKV-induced heart disease using mouse models and human cells, showing MAVS signaling is critical for viral clearance and preventing chronic vascular inflammation.

bioRxiv · May 27, 2022 · PreprintMicrobiology