Author

S. Olbrecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

D. Lambrechts· 2 shared I. Vergote· 2 shared A. Antoranz· 1 shared A. Bassez· 1 shared A. Franken· 1 shared A. Siekierska· 1 shared A. Smeets· 1 shared A. van den Broeck· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

D. Lambrechts

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Author profile →

2 papers

Recent·Most cited

The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells.

F. Claes, E. Maritschnegg, G. De Baets, A. Siekierska, M. Saiz Rubio, M. Ramakers, E. Michiels, F. De Smet, J. Depreeuw, I. Vergote, A. Vanderstichele, A. van den Broeck, S. Olbrecht, E. Hermans, F. Amant, , J. Schymkowitz

This study shows PTEN, a tumor suppressor, undergoes amyloid-like aggregation in tumor cells, both due to mutations and dysregulated protein homeostasis, and links this aggregation to poor clinical outcomes.

bioRxiv · Nov 30, 2020 · PreprintCancer Biology

A Pan-Cancer Blueprint of the Heterogeneous Tumour Microenvironment Revealed by Single-Cell Profiling

J. Qian, S. Olbrecht, B. Boeckx, H. Vos, D. Laoui, E. Etlioglu, E. Wauters, V. Pomella, S. Verbandt, P. Busschaert, A. Bassez, A. Franken, M. Vanden Bempt, J. Xiong, B. Weynand, , D. Lambrechts

This study profiles single cells from multiple cancer types to create a pan-cancer blueprint of stromal cell heterogeneity, identifying shared and unique cell populations and their characteristics.

bioRxiv · Apr 1, 2020Cancer Biology