Author

S. P. Guan

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. G. Lee· 1 shared H. Xia· 1 shared J. Hu· 1 shared J. Yap· 1 shared J. Yuan· 1 shared M. Baccarini· 1 shared M. Wang· 1 shared P. Y. P. Lam· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. S. G. Lee

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1 paper

Recent·Most cited

The Dimer-dependent Catalytic Activity of RAF Family Kinases Is Revealed Through Characterizing Their Oncogenic Mutants

J. Yuan, W. H. Ng, P. Y. P. Lam, Y. Wang, H. Xia, J. Yap, S. P. Guan, A. S. G. Lee, M. Wang, M. Baccarini, J. Hu

This study identifies dimer-dependent catalytic activity in RAF family kinases through analysis of oncogenic mutants, revealing differential inhibitor resistance and MEK phosphorylation mechanisms.

bioRxiv · Jun 4, 2018Cancer Biology