Broken force dispersal network in tip-links by the mutations induces hearing-loss
J. P. Hazra, A. Sagar, N. Arora, D. Deb, S. P. Kaur, S. Rakshit
The paper investigates how mutations in tip-link proteins disrupt force transmission in inner ear sensors, leading to hearing loss, and shows that Ca2+ can restore function in mutants.
bioRxiv · Apr 19, 2019Biophysics