Author

S. P. Mahan

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Baumler· 1 shared B. C. English· 1 shared B. H. Abuaita· 1 shared B. M. Young· 1 shared G. J. Sule· 1 shared H. P. Savage· 1 shared J. S. Knight· 1 shared M. X. O'Riordan· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. J. Baumler

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1 paper

Recent·Most cited

The IRE1α-XBP1 signaling axis promotes glycolytic reprogramming in response to inflammatory stimuli

B. C. English, H. P. Savage, S. P. Mahan, V. E. Diaz-Ochoa, B. M. Young, B. H. Abuaita, G. J. Sule, J. S. Knight, M. X. O'Riordan, A. J. Baumler, R. M. Tsolis

This study shows that the IRE1α-XBP1 signaling axis enhances glycolysis in macrophages during inflammation, but pathway activation alone is not sufficient to increase glycolytic rates.

bioRxiv · Oct 19, 2022Immunology