Deletion of Glyoxalase 1 exacerbates acetaminophen-induced hepatotoxicity in mice
P. Dobariya, W. Xie, S. P. Rao, J. Xie, D. M. Seelig, R. Vince, M. K. Lee, S. S. More
This study shows that deleting Glyoxalase 1 worsens acetaminophen-induced liver damage in mice by increasing oxidative stress and necrosis.
bioRxiv · Dec 21, 2023 · PreprintPharmacology & Toxicology