Author

D. T. Clarke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Idris· 1 shared A. Supramaniam· 1 shared B. M. Davis· 1 shared D. J. Rolfe· 1 shared F. L. Gervasio· 1 shared G. Kelly· 1 shared G. O. Fruhwirth· 1 shared I. Galdadas· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Idris

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

R. S. Iyer, S. R. Needham, I. Galdadas, B. M. Davis, S. K. Roberts, R. C. Man, L. C. Zanetti-Domingues, D. T. Clarke, G. O. Fruhwirth, P. J. Parker, D. J. Rolfe, F. L. Gervasio, M. L. Martin-Fernandez

This study identifies how the T766M-EGFR mutation promotes tumor growth by utilizing new oligomer assembly mechanisms in ligand-free EGFR.

bioRxiv · Jun 16, 2023 · PreprintCancer Biology

Intranasal delivery of lipid nanoparticle encapsulated SARS-CoV-2 and RSV-targeting siRNAs reduces lung infection

A. Supramaniam, Y. Tayyar, D. T. Clarke, G. Kelly, K. V. Morris, N. A. McMillan, A. Idris

This paper develops an intranasal lipid nanoparticle (LNP) delivery system for siRNAs targeting SARS-CoV-2 and RSV, showing effective reduction of lung infection in mice.

bioRxiv · Jul 25, 2022 · PreprintMicrobiology