cAMP signalling is required for the actions of IP3 on Ca2+-transients in cardiac atria and beating rate in sino-atrial node
R. A. Capel, T. Collins, S. J. Bose, S. Rajasundaram, T. Ayagama, M. Zaccolo, R. A. Burton, D. A. Terrar
The paper investigates the interaction between IP3 and cAMP signaling in cardiac atria and sino-atrial node, showing that IP3 enhances Ca2+ transients and beating rate through AC activation.
bioRxiv · Jul 24, 2019 · PreprintPhysiology