R. A. Burton

Lysosomal calcium loading promotes arrhythmias by potentiating ryanodine receptor release

This study shows lysosomal calcium handling promotes RyR spontaneous release by increasing SR-junction calcium gradient, and blocking lysosomal function reduces arrhythmias.

The p-coumaroyl arabinoxylan transferase HvAT10 underlies natural variation in whole-grain cell wall phenolic acids in cultivated barley

The paper identifies HvAT10 as a gene responsible for natural variation in cell wall phenolic acids in barley, showing a premature stop codon mutation reduces its function and affects grain quality.

GWAS reveals the genetic complexity of fructan accumulation patterns in barley grain

This study identifies genetic factors influencing fructan accumulation patterns in barley grain through GWAS and co-expression analysis, revealing new gene candidates and distinct biosynthesis pathways.

Cellular debris, not mucilage polysaccharides, dominate extracts of Plantago ovata and Plantago lanceolata calli grown in vitro

The paper replicates mucilage extraction from Plantago ovata and P. lanceolata calli and finds that cellular debris, not mucilage polysaccharides, dominates the extracts.

Targeted mutation of barley (1,3;1,4)-β-glucan synthases reveals complex relationships between the storage and cell wall polysaccharide content

This study uses CRISPR/Cas9 to mutate barley Csl genes, revealing that HvCslF6 is essential for (1,3;1,4)-β-glucan synthesis while other family members affect cell wall composition and grain morphology.

cAMP signalling is required for the actions of IP3 on Ca2+-transients in cardiac atria and beating rate in sino-atrial node

The paper investigates the interaction between IP3 and cAMP signaling in cardiac atria and sino-atrial node, showing that IP3 enhances Ca2+ transients and beating rate through AC activation.