Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
M. Caligaris, R. Nicastro, Z. Hu, F. Tripodi, J. E. Hummel, M.-A. Deprez, J. Winderickx, S. Rospert, P. Coccetti, J. Dengjel, C. De Virgilio
This study shows Snf1/AMPK inhibits TORC1 during glucose starvation via Pib2 and Sch9 phosphorylation, integrating glucose and glutamine signals to regulate cell growth.
bioRxiv · Oct 18, 2022Biochemistry