Dual RNAseq of human leprosy lesions identifies bacterial determinants linked to host immune response
D. Montoya, P. R. Andrade, B. J. A. Silva, R. M. B. Teles, B. Bryson, S. Sadanand, T. Noel, J. Lu, E. Sarno, K. B. Arnvig, D. Young, R. Lahiri, D. L. Williams, S. Fortune, B. R. Bloom, , R. L. Modlin
The paper uses dual RNAseq to analyze leprosy lesions, linking bacterial states to host immune responses through type I IFNs and antibody pathways.
bioRxiv · Jun 22, 2018Microbiology