TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway
P. V. Iyengar, D. L. Marvin, D. Lama, T. Z. Tan, S. Suriyamurthy, F. Xie, M. van Dinther, H. Mei, C. S. Verma, L. Zhang, L. Ritsma, P. ten Dijke
This study identifies TRAF4 as a tumor suppressor in bladder cancer that promotes BMP/SMAD signaling and inhibits metastasis by targeting SMURF1 for degradation.
bioRxiv · Oct 12, 2020 · PreprintCancer Biology