Microbiota induces aging-related leaky gut and inflammation by dampening mucin barriers and butyrate-FFAR2/3 signaling
S. P. Mishra, B. Wang, S. Wang, R. Nagpal, B. Miller, S. Jain, J. Y. Lee, C. Borlongan, S. Taraphder, S. G. Rane, H. Yadav
The paper shows that aged microbiota causes leaky gut and inflammation by reducing butyrate and FFAR2/3, which weakens mucin barriers.
bioRxiv · Aug 18, 2021 · PreprintPhysiology