Author

S. Taschner-Mandl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1

Frequent Co-Authors

F. Rifatbegovic· 4 shared F. Halbritter· 3 shared I. M. Ambros· 3 shared P. F. Ambros· 3 shared R. Ladenstein· 3 shared A. Bileck· 2 shared C. Gerner· 2 shared D. Lazic· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCancer Biology

F. Rifatbegovic

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cross-species analysis identifies conserved transcriptional mechanisms of neutrophil maturation

S. Kirchberger, M. R. Shoeb, D. Lazic, K. Fischer, L. E. Shaw, F. Nogueira, F. Rifatbegovic, E. Bozsaky, R. Ladenstein, B. Bodenmiller, T. Lion, D. Traver, M. Farlik, S. Taschner-Mandl, F. Halbritter, M. Distel

The paper identifies conserved transcriptional mechanisms of neutrophil maturation across zebrafish, mouse, and human by generating high-resolution transcriptional profiles and cross-species comparisons.

bioRxiv · Nov 28, 2022Immunology

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

I. M. Saldana-Guerrero, L. F. Montano-Gutierrez, K. Boswell, C. Hafemeister, E. Poon, L. E. Shaw, D. Stavish, R. A. Lea, S. Wernig-Zorc, E. Bozsaky, I. S. Fetahu, P. Zoescher, U. Pötschger, M. Bernkopf, A. Wenninger-Weinzierl, , F. Halbritter

The paper uses human embryonic stem cells to show that chromosomal gains in neuroblastoma impair neural crest development and enhance MYCN-driven tumourigenesis.

bioRxiv · Nov 21, 2022Cancer Biology

Human repair-related Schwann cells adopt functions of antigen-presenting cells in vitro

J. Berner, T. Weiss, H. Sorger, F. Rifatbegovic, M. Kauer, R. Windhager, A. Dohnal, P. F. Ambros, I. M. Ambros, P. Steinberger, S. Taschner-Mandl

This study shows human repair-related Schwann cells exhibit antigen-presenting cell features and suppress T-cell activation in vitro.

bioRxiv · Mar 7, 2022Cell Biology

Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8

T. Weiss, S. Taschner-Mandl, A. Bileck, F. Rifatbegovic, H. Sorger, M. Kauer, C. Frech, R. Windhager, C. Gerner, P. F. Ambros, I. M. Ambros

This study shows that Schwann cells in neuroblastic tumors and injured nerves share repair-related functions, with EGFL8 promoting neuronal differentiation of tumor cells.

Nature Communications · Mar 12, 2021Peer-reviewedCancer Biology

Single-cell landscape of bone marrow metastases in human neuroblastoma unraveled by deep multiplex imaging

D. Lazic, F. Kromp, M. Kirr, F. Mivalt, F. Rifatbegovic, F. Halbritter, M. Bernkopf, A. Bileck, M. Ussowicz, I. M. Ambros, P. F. Ambros, C. Gerner, R. Ladenstein, C. Ostalecki, S. Taschner-Mandl

This study uses deep multiplex imaging to create a single-cell atlas of bone marrow metastases in neuroblastoma, revealing tumor heterogeneity and microenvironmental changes.

bioRxiv · Sep 30, 2020 · PreprintCancer Biology