Author

L. E. Shaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:scRNA-seq· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Farlik· 4 shared W. Weninger· 3 shared E. Bozsaky· 2 shared F. Halbritter· 2 shared M. Distel· 2 shared M. R. Shoeb· 2 shared R. Ladenstein· 2 shared S. Taschner-Mandl· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersCancer Biology

M. Farlik

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation

J. Griss, S. Gansberger, I. Oyarzun, M. C. Drach, V. Nguyen, L. E. Shaw, U. Mann, S. Porkert, M. Farlik, W. Weninger, W. Dolak, B. Aschenbrenner, B. M. Lichtenberger, C. Wagner, I. Simonitsch-Klupp, , P. M. Brunner

This study uses single-cell RNA sequencing to compare indolent primary cutaneous B-cell lymphomas with other B-cell proliferations, finding they resemble persistent antigen reactions with germinal center features.

bioRxiv · Dec 16, 2022 · PreprintCancer Biology

Cross-species analysis identifies conserved transcriptional mechanisms of neutrophil maturation

S. Kirchberger, M. R. Shoeb, D. Lazic, K. Fischer, L. E. Shaw, F. Nogueira, F. Rifatbegovic, E. Bozsaky, R. Ladenstein, B. Bodenmiller, T. Lion, D. Traver, M. Farlik, S. Taschner-Mandl, F. Halbritter, M. Distel

The paper identifies conserved transcriptional mechanisms of neutrophil maturation across zebrafish, mouse, and human by generating high-resolution transcriptional profiles and cross-species comparisons.

bioRxiv · Nov 28, 2022Immunology

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

I. M. Saldana-Guerrero, L. F. Montano-Gutierrez, K. Boswell, C. Hafemeister, E. Poon, L. E. Shaw, D. Stavish, R. A. Lea, S. Wernig-Zorc, E. Bozsaky, I. S. Fetahu, P. Zoescher, U. Pötschger, M. Bernkopf, A. Wenninger-Weinzierl, , F. Halbritter

The paper uses human embryonic stem cells to show that chromosomal gains in neuroblastoma impair neural crest development and enhance MYCN-driven tumourigenesis.

bioRxiv · Nov 21, 2022Cancer Biology

A distinct CD115- erythro-myeloid precursor present at the maternal-embryonic interface and in the bone marrow of adult mice

S. Tikoo, R. Jain, B. Martinez, R. Song, M. Wielscher, S. Rizzetto, L. E. Shaw, A. J. Mitchell, M. E. Torres-Pacheco, F. Luciani, M. Farlik, J. Wong, S. Jung, S. T. Fraser, W. Weninger

The paper identifies a CD115- macrophage precursor in adult bone marrow that shares features with embryonic erythro-myeloid progenitors and is present at the maternal-embryonic interface.

bioRxiv · Jul 24, 2021 · PreprintImmunology