Author

R. Kaiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Leunig· 3 shared K. Pekayvaz· 3 shared K. Stark· 3 shared L. Nicolai· 3 shared S. Massberg· 3 shared V. Polewka· 3 shared L. Eivers· 2 shared M. Joppich· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Leunig

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation

M. S. J. Mangan, A. Akbal, S. Rivara, A. Schroeder, G. L. Horvath, P. Walch, J. Hegermann, R. Kaiser, F. Duthie, J. Selkrig, J. Jantsch, R. Gerhard, D. Wachten, E. Latz

The paper shows that cytosolic sodium accumulation triggers NLRP3 inflammasome activation in response to various danger signals in human macrophages.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis

K. Pekayvaz, M. Joppich, S. Brambs, V. Knottenberg, L. Eivers, A. Martinez-Navarro, R. Kaiser, N. Meissner, B. Kilani, S. Stockhausen, A. J. Janjic, V. Polewka, F. W. Wendler, A. D. zu Senden, A. Leunig, , K. Stark

The paper maps immune cell trajectories and interactions in human thrombi, identifying prothrombotic and thrombolytic monocyte and neutrophil subsets with therapeutic implications.

bioRxiv · Jan 10, 2024 · PreprintImmunology

Thrombocytopenia and splenic platelet directed immune responses after intravenous ChAdOx1 nCov-19 administration

L. Nicolai, A. Leunig, K. Pekayvaz, A. Anjum, E. Riedlinger, L. Eivers, M.-L. Hoffknecht, D. Rossaro, R. Escaig, R. Kaiser, V. Polewka, A. Titova, K. Spiekermann, M. Iannacone, K. Stark, S. Massberg

This study investigates how intravenous ChAdOx1 nCov-19 vaccination leads to thrombocytopenia and immune responses against platelets, suggesting intramuscular injection as a safer alternative.

bioRxiv · Jun 29, 2021Immunology

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection

K. Pekayvaz, A. Leunig, R. Kaiser, S. Brambs, M. Joppich, A. Janjic, O. Popp, V. Polewka, L. E. Wange, C. Gold, M. Kirchner, M. Muenchhoff, J. C. Hellmuth, C. Scherer, T. Eser, , L. Nicolai

This study identifies an early interferon-stimulated gene (ISG) upregulation as a protective immune signature in non-pneumonic SARS-CoV-2 infection, preventing progression to pneumonia.

bioRxiv · Feb 3, 2021Immunology