Adjuvant Discovery via a High Throughput Screen using Human Primary Mononuclear Cells
K. Chew, B. Lee, S. Van Haren, E. Nanishi, T. R. O'Meara, J. B. Splaine, M. De Leon, D. Soni, H.-S. R. Seo, S. Dhe-Paganon, A. Ozonoff, J. A. Smith, O. Levy, D. J. Dowling
This paper describes a high-throughput screening method using human PBMCs to identify adjuvant candidates, resulting in a lead compound with in vivo adjuvanticity.
bioRxiv · Jun 17, 2022 · PreprintImmunology