Reduced non-specific binding of super-resolution DNA-PAINT markers by Shielded DNA-PAINT labeling protocols
E. Lucinskaite, A. F. E. Bokhobza, A. Stannard, A. Meletiou, C. Estell, S. West, L. Di Michele, C. Soeller, A. H. Clowsley
The paper introduces Shielded DNA-PAINT, a method to reduce non-specific DNA-PAINT probe binding in cells, achieving a 5-fold reduction in non-specific events in the nucleus.
bioRxiv · Jun 3, 2024Biophysics