Author

S. Wiechmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Ernst· 1 shared B. M. Grebbin· 1 shared F. Sicheri· 1 shared H. Clevers· 1 shared H. F. Farin· 1 shared I. Kurinov· 1 shared K. Rajalingam· 1 shared M. Hoffmeister· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Ernst

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1 paper

Recent·Most cited

Novel Conformation Specific Inhibitors of Activated GTPases reveal Ras-dependency of Patient-Derived Cancer Organoids

S. Wiechmann, P. Maisonneuve, B. M. Grebbin, M. Hoffmeister, M. Kaulich, H. Clevers, K. Rajalingam, I. Kurinov, H. F. Farin, F. Sicheri, A. Ernst

The paper develops RBD variants that inhibit Ras effector binding, inducing senescence in non-tumorigenic cells and revealing Ras dependency in cancer organoids.

bioRxiv · Aug 28, 2019Cancer Biology