Author

S. Y. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

S. Lee· 2 shared A. Chalk· 1 shared A. G. Kulasekararaj· 1 shared A. R. Wu· 1 shared A. Torres· 1 shared A. Unnikrishnan· 1 shared B. T. K. Lee· 1 shared B. Wang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

S. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromes.

S. Y. Tan, C. Joseph, M. L. Sobah, A. Chalk, K. Schleibs, S. Lee, G. Tjin, S. Chugh, X. Mo, C. Grace, J. Q. Truong, M. F. Smeets, K. Rice, M. Parker, A. Unnikrishnan, , L. Purton

This study shows that dysregulated Hoxa1 isoforms in hematopoietic stem and progenitor cells cause myelodysplastic syndromes and provide mouse models for disease progression.

bioRxiv · Apr 24, 2023 · PreprintCancer Biology

Transcriptomic Analysis of 3D Vasculature-On-A-Chip Reveals Paracrine Factors Affecting Vasculature Growth and Maturation

A. R. Wu, S. Y. Tan, Q. Jing, Z. Leung, Y. Xu

The paper uses a microfluidic platform to study paracrine interactions between human microvasculature and fibroblasts, identifying growth factors and cytokines that enhance vasculature growth.

bioRxiv · Nov 21, 2021Bioengineering

Neutralizing antibodies from early cases of SARS-CoV-2 infection offer cross-protection against the SARS-CoV-2 D614G variant.

C. Y.-P. Lee, S. N. Amrun, R. S.-L. Chee, Y. S. Goh, T. M. Mak, S. Octavia, N. Yeo, Z. W. Chang, M. Z. Tay, A. Torres, G. Carissimo, C. M. Poh, S.-W. Fong, B. Wang, S. Lee, , L. F. P. Ng

This study shows that antibodies from early SARS-CoV-2 infections neutralize both the original and D614G variants, though neutralizing capacity decreases over time.

bioRxiv · Oct 8, 2020 · PreprintImmunology