Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice
E. Yamasaki, P. Thakore, S. Ali, A. S. Solano, X. Wang, X. Gao, C. Labelle-Dumais, M. M. Chaumeil, D. B. Gould, S. Earley
This study identifies impaired SR Ca2+ signaling and disrupted ion channel activity in Col4a1 mutant mice as contributors to age-related cerebral small vessel disease.
bioRxiv · Aug 24, 2022 · PreprintPathology